[Severe acute respiratory syndrome: the first transmissible disease of the 21st century].
Identifieur interne : 006680 ( Main/Exploration ); précédent : 006679; suivant : 006681[Severe acute respiratory syndrome: the first transmissible disease of the 21st century].
Auteurs : Emanuele Nicastri [Italie] ; Nicola Petrosillo ; Giulia Macrì ; Giuseppe IppolitoSource :
- Recenti progressi in medicina [ 0034-1193 ]
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Algorithmes, Antiviraux (administration et posologie), Antiviraux (usage thérapeutique), Chine (épidémiologie), Facteurs temps, Hong Kong (épidémiologie), Humains, Organisation mondiale de la santé, Ribavirine (administration et posologie), Ribavirine (usage thérapeutique), Santé mondiale, Sujet âgé, Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (transmission), Syndrome respiratoire aigu sévère (épidémiologie), Voyage.
- MESH :
- administration et posologie : Antiviraux, Ribavirine.
- diagnostic : Syndrome respiratoire aigu sévère.
- traitement médicamenteux : Syndrome respiratoire aigu sévère.
- usage thérapeutique : Antiviraux, Ribavirine, Syndrome respiratoire aigu sévère.
- épidémiologie : Chine, Hong Kong, Syndrome respiratoire aigu sévère.
- Adulte, Adulte d'âge moyen, Algorithmes, Facteurs temps, Humains, Organisation mondiale de la santé, Santé mondiale, Sujet âgé, Voyage.
- Wicri :
- geographic : République populaire de Chine, Hong Kong.
English descriptors
- KwdEn :
- Adult, Aged, Algorithms, Antiviral Agents (administration & dosage), Antiviral Agents (therapeutic use), China (epidemiology), Global Health, Hong Kong (epidemiology), Humans, Middle Aged, Ribavirin (administration & dosage), Ribavirin (therapeutic use), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (transmission), Time Factors, Travel, World Health Organization.
- MESH :
- chemical , administration & dosage : Antiviral Agents, Ribavirin.
- chemical , therapeutic use : Antiviral Agents, Ribavirin.
- geographic , epidemiology : China, Hong Kong.
- diagnosis : Severe Acute Respiratory Syndrome.
- drug therapy : Severe Acute Respiratory Syndrome.
- epidemiology : Severe Acute Respiratory Syndrome.
- transmission : Severe Acute Respiratory Syndrome.
- Adult, Aged, Algorithms, Global Health, Humans, Middle Aged, Time Factors, Travel, World Health Organization.
Abstract
The Severe Acute Respiratory Syndrome (SARS) is the first severe and easily transmissible disease to emerge in the 21st century. It is caused by the infection with a coronavirus, a single strand RNA capsulated virus, recently found in a small mammalian, the masked palm civet. It is likely to represent the source of human infection. The first cases of SARS have been reported in the Chinese province of Guangdong and, since then, probable cases have been reported world wide. The clinical picture is characterized by nonspecific symptoms such as fever, cough or dyspnea in patients affected by air-space opacities (unifocal involvement in the 54.6% of cases) or distress respiratory syndrome and linked to a recent exposure to a SARS case or to a travel/residence in an affected area. The empirical therapy is based on broad-spectrum antibiotics, steroids and ribavirin, but susceptibility testing have failed to demonstrate direct anti-viral activity of ribavirin against SARS-related coronavirus in vitro. The exposure to respiratory droplets and the contact with biologic fluids (respiratory and gastrointestinal secretions) represent the most efficient transmission modality of the SARS-related coronavirus. Hand hygiene is the most simple and cost effective measure of infection control to prevent contagion, and the use of airborne, contact and droplet precaution is strictly recommended to all health care workers taking care of such patients. The spread of SARS, to less developed country with limited resource for public health programs, represent the emerging alarming threat in the new global scenario.
PubMed: 12868234
Affiliations:
Links toward previous steps (curation, corpus...)
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Le document en format XML
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The exposure to respiratory droplets and the contact with biologic fluids (respiratory and gastrointestinal secretions) represent the most efficient transmission modality of the SARS-related coronavirus. Hand hygiene is the most simple and cost effective measure of infection control to prevent contagion, and the use of airborne, contact and droplet precaution is strictly recommended to all health care workers taking care of such patients. The spread of SARS, to less developed country with limited resource for public health programs, represent the emerging alarming threat in the new global scenario.</div></front></TEI><affiliations><list><country><li>Italie</li></country><region><li>Latium</li></region><settlement><li>Rome</li></settlement></list><tree><noCountry><name sortKey="Ippolito, Giuseppe" sort="Ippolito, Giuseppe" uniqKey="Ippolito G" first="Giuseppe" last="Ippolito">Giuseppe Ippolito</name><name sortKey="Macri, Giulia" sort="Macri, Giulia" uniqKey="Macri G" first="Giulia" last="Macrì">Giulia Macrì</name><name sortKey="Petrosillo, Nicola" sort="Petrosillo, Nicola" uniqKey="Petrosillo N" first="Nicola" last="Petrosillo">Nicola Petrosillo</name></noCountry><country name="Italie"><region name="Latium"><name sortKey="Nicastri, Emanuele" sort="Nicastri, Emanuele" uniqKey="Nicastri E" first="Emanuele" last="Nicastri">Emanuele Nicastri</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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